Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. Rare, long-term side effects of Prolia include fractures of the spine or femur (thighbone). Prolia can also cause bones to not form correctly and reduced growth in a fetus. So treatment with the drug requires you to take daily calcium and vitamin D supplements. With arthritis, you have pain and inflammation of your joints. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. They include bone pain, back pain, and a higher risk of certain infections. But if you look at D3 supplements online, youll see that most commercial supplements have higher doses usually either 1,000, 2,000, 5,000 or 10,000 IU. These supplements help to prevent a low calcium level while youre taking Prolia. Compared to other osteoporosis treatments, only Proliais1 shot every 6 months. Get emergency medical help if you have signs of an allergic reaction to Prolia: hives, itching, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat. If your levels are high, theyll typically recommend lifestyle changes and medication. For instance: Both Prolia and Forteo are given as injections under your skin. The most common side effects of Prolia in patients with corticosteroid-induced osteoporosis are back pain, high blood pressure, lung infection (bronchitis), and headache. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The drug may also be used off-label for osteopenia, but usually, you dont need medications for osteopenia. Having dental procedures, including tooth extractions, during Prolia treatment may increase your risk of dental side effects. What should be considered before taking Prolia? These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. Your doctor or another healthcare professional will inject Prolia under the skin in one of the following areas: Prolia doses are given as an injection by healthcare professionals once every 6 months. Ask your doctor about the pros and cons of using Prolia. If youre concerned about side effects with Prolia, talk with your doctor. But if your symptoms are serious and you think youre having a medical emergency, immediately call 911 or your local emergency number. You can also visit the Prolia manufacturers website to see if they have support options. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Instead, it belongs to a different group of medications called biologics. But if youre planning to have surgery, you may need to take a break If you dont understand something related to your condition or treatment, ask your doctor to explain it to you. (Biosimilars are like generic drugs. It blocks the effects of certain bone cells called osteoclasts in breaking down bone tissue. The conditions and factors to consider include: Upcoming dental procedures. If you cant properly absorb calcium or other minerals, be sure to talk with your doctor before using Prolia. You can learn more about how we ensure our content is accurate and current by reading our. All subjects in the clinical trials of Prolia received 800mg of calcium and You are encouraged to report negative side effects of prescription drugs to the FDA. Prolia pregnancy and breastfeeding warnings. If you develop high cholesterol with Prolia, your doctor can guide you on which treatment options are right for your condition. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. Drug class: Miscellaneous bone resorption inhibitors. Some items may interact with your medicine. Serious side effects that have been reported and their symptoms include: * To learn more, see Does Prolia cause long-term side effects? in the FAQs about the side effects of Prolia section below. You may take the carton out of the refrigerator and allow it to reach room temperature before the injection is given. If you develop a side effect while taking Prolia and want to tell the FDA about it, visit MedWatch. for breast cancer that has not spread to other parts of the body. It is often used in osteoporosis. This may help to protect healthy cells from damage. Do not shake the prefilled syringe. Every 6 months youll get another dose of Prolia. Talk to your health care professional or pharmacist for more information. Youll receive Prolia doses from a healthcare professional. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Prolia is usually given once every 6 months. You should not breastfeed while using this medicine. Youll likely have questions about your condition and treatment choices. Before taking Prolia, tell your doctor about all of your medical conditions, including if you: Your healthcare provider should do a pregnancy test before you start treatment with Prolia. Prolia should not be used during pregnancy. Boniva contains the active drug ibandronate, but Prolia contains the active drug denosumab. And theyll recommend if its the best option for your condition. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. Some people may have dental or jaw-related issues with Prolia use. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. A biologic drug is made from parts of living organisms. And in my mind, that's no different than scheduling a visit to the dentist twice a year. But if you think youre having a medical emergency, call 911 or your local emergency number. But it can increase your risk of serious health problems, such as heart attack. If your dizziness doesnt go away or becomes severe, talk with your doctor. They can suggest ways to help relieve these side effects. for prostate cancer that has not spread to other parts of the body. Forteo is given as a self-injection once daily. Available for Android and iOS devices. The drug stays in your system and continues to slow bone breakdown over this period of time. Prolia may cause serious side effects. Visit www.fda.gov/medwatch, orcall1-800-FDA-1088. Its a, Forteos active ingredient is teriparatide. This drug may not be the right treatment for your condition if you have certain medical conditions or other factors that affect your health. And some of these side effects are more common with certain uses of Prolia. But weight gain may be a symptom of a side effect called peripheral edema. What should I know about Prolia vs. Tymlos? Hair loss with Prolia is rare, and whether Prolia is responsible for this effect isnt known. Your FRAX score is your risk of having an osteoporosis-related fracture in the next 10 years. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. Prolia is used to treat osteoporosis in women after menopause and in men, and in people who are taking corticosteroids for 6 months or more. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed. If youre concerned about unexplained weight gain while using Prolia, talk with your doctor. Learn how estrogen affects bone health and how you can protect yourself from bone loss, Osteoporosis is more common in women than men, but it affects millions of men every year. Throw away a prefilled syringe after one use, even if there is still medicine left inside. Studies of Prolia didnt report weight gain as a side effect of the drug. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Prolia injection is a brand of denosumab, which treats osteoporosis. A special MedGuide will be given to you before each treatment. such as inflammation of your skin (dermatitis), rash, and eczema have been reported. Prolia contains the active drug denosumab, while Tymlos contains the active drug abaloparatide. We do not endorse non-Cleveland Clinic products or services. Prolia is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines (such as prednisone) for at least six months and are at high risk for fracture. (Biosimilars are like generic drugs. Before you start Prolia treatment, talk with your doctor about how long Prolias side effects may last. It is given by a health care professional in a hospital or clinic setting. Learn more about the FRAX score and the treatment options for, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Tell your doctor if you become pregnant. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Prolia is injected under the skin. They may also have you see your dentist. Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. Youll likely receive Prolia long term if you and your doctor decide that the drug is effective and safe for you. Calcium and Vitamin D: A major role of vitamin D is to help the body absorb calcium and maintain bone density. The Prolia is making my leg bones and jaw bones hurt. As you age, your BMD is reduced, and this may increase your risk for osteoporosis. Youll receive 60 mg/mL of Prolia once every 6 months. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. * Sex and gender exist on spectrums. But if they become bothersome, talk with your doctor or pharmacist. Prolia also has other uses, which are described in the next section below. Some rare side effects of Prolia can be serious and need medical attention. They need to know if you have any of these conditions: This medicine is for injection under the skin. These side effects may include: Its not known what percentage of people in clinical trials developed dental or jaw-related side effects. Over time, Prolia helps to improve the density and strength of your bones by slowing bone loss. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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